Research Technician (SRI) - Microscopy Imaging and Histology - Regular Full-time 2024-9387

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Date Posted: 6/19/2024

Location: Toronto, ON, Canada

Reference No.: 2024-9387

Position Type: Regular full-time


FTE Status: 1.00

Hours of Work: Other

Campus Site: Other

Shifts Weekday Required: Other

Shifts Weekend Required: Other

Statutory Holiday(s) Required: No

We are seeking an exceptional Microscopy Imaging Research Technician to join our cutting-edge neuroscience research team at Sunnybrook Research Institute in Toronto, Canada, in the laboratory of Dr. Isabelle Aubert. This is an outstanding opportunity for a highly skilled and motivated individual to utilize advanced microscopy techniques and drive innovative discoveries in the preclinical development of brain therapies for neurodegenerative disorders.




1. Imaging

a.  Operate and maintain the Leica Stellaris 5 White Light Microscope

b.  Ensure proper maintenance, calibration, and troubleshooting of imaging equipment

c.  Acquire images on the Leica Stellaris 5 and analyze them with specialized software


2. Histology

a.  Process, cut and stain brain, spinal cord and other tissue for imaging

b.  Perform immunohistochemistry and RNAscope experiments


3. General

a.  Develop and optimize imaging, analyses and histology protocols and stay up to date with technological and methodological advancements

b.  Maintain detailed records and documentation of experiments, imaging and quantification procedures and results

c.  Train and supervise users

d.  Ensure compliance with laboratory safety protocols and ethical standards



  • Degree in Neuroscience, Biology, Biomedical Engineering, or a related field
  • Extensive hands-on experience with state-of-the-art confocal microscope, such as the Leica Stellaris 5 White Light Microscope or equivalent
  • Expertise in Tausense microscopy or equivalent
  • Proficiency in 2D and 3D image imaging, analysis and quantification
  • Expertise with LASX, ImageJ (FIJI), Cell Profiler, Illustrator, Photoshop, Zenblue, and other software
  • Hands-on experience with histology, including brain tissue processing, sectioning, staining, and slide preparation.
  • Expertise in immunohistochemistry and RNAscope techniques in rodent models
  • Excellent problem-solving and analytical skills
  • Ability to work independently and as part of a collaborative research team
  • Strong organizational and time management skills
  • Excellent written and verbal communication abilities



At Sunnybrook Research Institute in Toronto, we offer a competitive compensation package, opportunities for professional growth, and a dynamic neuroscience research environment. This Research Technician position is currently open, and applicants will be considered until it is filled. The salary depends on qualification, at a minimum of $48,750 per year ($25/hour). We encourage you to apply if you are passionate about cutting-edge imaging technologies and eager to contribute to groundbreaking neuroscience research.


To apply, please submit your cover letter, resume, contact information for three professional references and a statement describing your relevant experience and research interests. Send your application to Dr. Isabelle Aubert (, and Dr. Nathalie Vacaresse (





If you are looking for an exciting opportunity and to build a career in an innovative and dynamic organization, submit your resume by clicking on Apply Now below. 

Sunnybrook Health Sciences Centre is committed to providing accessible employment practices that are in compliance with the Accessibility for Ontarians with Disabilities Act (AODA). If you require accommodation for disability during any stage of the recruitment process, please indicate this in your cover letter.

Sunnybrook Health Sciences Centre is strongly committed to inclusion and diversity within its community and welcomes all applicants including but not limited to: visible minorities, all religions and ethnicities, persons with disabilities, LGBTQ persons, and all others who may contribute to the further diversification of ideas.

Please be advised that in order to be eligible for employment at Sunnybrook, all new hires must have received the full series of a COVID-19 vaccine or combination of COVID-19 vaccines approved by Health Canada (e.g., two doses of a two-dose vaccine series, or one dose of a single-dose vaccine series); AND have received the final dose of the COVID-19 vaccine at least 14 days ago. Medical exemptions or any other kind of requested exemption based upon the Hospital’s obligations pursuant to the Ontario Human Rights Code will be considered on a case-by-case basis.

We thank all applicants for their interest. However, only candidates selected for an interview will be contacted. Sunnybrook Health Sciences Centre is an equal opportunity employer.